On May 24, 2003 in Tbilisi, Georgia, the GUUAM Countries and the United States continued their dialogue on their common goals of combating terrorism, transnational crime, enhancing border security and customs control and encouraging trade at the Third Meeting of the Council of Ministers for Foreign Affairs of GUUAM Countries.

On September 26, a new round of U.S.-GUUAM dialogue at the Ministerial level was held during the General Debates of the 58 Session of the United Nations General Assembly.
High representatives of the GUUAM member states and the U.S. discussed U.S.-GUUAM cooperation and progress on the U.S.-GUUAM Framework Program.

On April 21 and 22, 2005 in Chisinau, Moldova, the GUUAM Participating States and the United States met to advance their dialogue and cooperation at the Ninth Meeting of the Council of Ministers for Foreign Affairs of GUUAM Countries, on April 21, and the GUUAM Summit of Heads of State, on April 22. Ambassador Steven Mann, Senior Advisor for Eurasia, led the U.S. delegation.

On May 22-23, 2006 in Kyiv, Ukraine, the GUAM Member-States and the United States met at the Eleventh Meeting of the Council of Ministers for Foreign Affairs of GUAM and the GUAM Summit to continue their dialogue and cooperation. The U.S. delegation was led by David J. Kramer, Deputy Assistant Secretary for European and Eurasian Affairs.

On June 18, 2007 in Baky, Azerbaijan, a regular GUAM-USA meeting was held within the framework of the second Summit of the Organization for Democracy and Economic Development – GUAM.
The United States reiterated its long-standing support to and interest in GUAM’s further development as regional organization and its active contribution into international affairs.

On October 30, 2007 a meeting of GUAM National Coordinators and the GUAM Secretary General was held with senior officials of the U.S. Department of State and the U.S.

On September 23rd, 2008 in New York, 14th meeting of the GUAM Council of the Ministers of Foreign Affairs – United States of America was held within the framework of the general debates of the 63rd Session of the General Assembly of the United Nations.
The sides reiterated the consistent and sustainable character of GUAM – United States political dialogue.

On September 25, 2009 in New York, 16th meeting of the GUAM Council of the Ministers for Foreign Affairs – the United States of America was held within the framework of the general debates on the 64th session of the General Assembly of the United Nations.
The sides assessed their cooperation following the last GUAM – United States Ministerial meeting in Helsinki on December 4, 2008 and underlin